Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery

Abstract Background The objectives of the study were to characterize and quantify cellular inflammation and structural remodeling of human atria and correlate findings with molecular markers of inflammation and patient surrogate outcome. Methods Voluntary participants undergoing heart surgery were e...

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Detalhes bibliográficos

Principais autores:	Christie M. Aguiar, Kareem Gawdat, Stephanie Legere, Jean Marshall, Ansar Hassan, Petra C. Kienesberger, Thomas Pulinilkunnil, Mathieu Castonguay, Keith R. Brunt, Jean-Francois Legare
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-12-01
coleção:	Journal of Translational Medicine
Assuntos:	Atrial fibrillation Cytokines Macrophages (MoΦ) Human atrium Cardiac surgery Leucocyte infiltration
Acesso em linha:	https://doi.org/10.1186/s12967-019-02162-5
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