Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines

Abstract Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Although standard-of-care chemotherapeutics are sufficient for most ALL cases, there are subsets of patients with poor response who relapse in disease. The biology underlying differences between subtypes and their respo...

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Hlavní autoři:	Isabelle Rose Leo, Luay Aswad, Matthias Stahl, Elena Kunold, Frederik Post, Tom Erkers, Nona Struyf, Georgios Mermelekas, Rubin Narayan Joshi, Eva Gracia-Villacampa, Päivi Östling, Olli P. Kallioniemi, Katja Pokrovskaja Tamm, Ioannis Siavelis, Janne Lehtiö, Mattias Vesterlund, Rozbeh Jafari
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2022-03-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-022-29224-5
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