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suPAR, a Circulating Kidney Disease Factor

Urokinase plasminogen activator receptor (uPAR) is a multifaceted, GPI-anchored three-domain protein. Release of the receptor results in variable levels of soluble uPAR (suPAR) in the blood circulation. suPAR levels have been linked to many disease states. In this mini-review, we discuss suPAR as a...

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Principais autores: Changli Wei, Ryan Spear, Eunsil Hahm, Jochen Reiser
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-10-01
Serier:Frontiers in Medicine
Fag:
suPAR
isoform
proteinuric disease
kidney
uPAR
Online adgang:https://www.frontiersin.org/articles/10.3389/fmed.2021.745838/full
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