The dose-dependent dual effects of alpha-ketoglutarate (AKG) on cumulus oocyte complexes during in vitro maturation

Abstract In this study, we reported for the first time the dose-dependent dual effects of Alpha-Ketoglutarate (AKG) on cumulus oocyte complexes (COCs) during in vitro maturation (IVM). AKG at appropriate concentration (30 µM) has beneficial effects on IVM. This includes improved cumulus expansion, o...

Descripció completa

Dades bibliogràfiques

Autors principals:	Yunjie Liu, Xin Xiao, Likai Wang, Yao Fu, Songyang Yao, Xuening Liu, Boda Chen, Jiarui Gao, Yaying Zhai, Zixia Shen, Laiqing Yan, Yiwei Wang, Pengyun Ji, Bingyuan Wang, Guoshi Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-10-01
Col·lecció:	Cell Communication and Signaling
Matèries:	Alpha-ketoglutarate Cumulus oocyte complexes In vitro maturation Reactive oxygen species Cumulus cells-oocyte communication
Accés en línia:	https://doi.org/10.1186/s12964-024-01827-z
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!