Spatial distribution of tumour immune infiltrate predicts outcomes of patients with high-risk soft tissue sarcomas after neoadjuvant chemotherapyResearch in context

Summary: Background: Anthracycline-based neoadjuvant chemotherapy (NAC) may modify tumour immune infiltrate. This study characterized immune infiltrate spatial distribution after NAC in primary high-risk soft tissue sarcomas (STS) and investigate association with prognosis. Methods: The ISG-STS 100...

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Autors principals:	Sandro Pasquali, Viviana Vallacchi, Luca Lalli, Paola Collini, Marta Barisella, Cleofe Romagosa, Silvia Bague, Jean Michel Coindre, Angelo Paolo Dei Tos, Emanuela Palmerini, Vittorio Quagliuolo, Javier Martin-Broto, Antonio Lopez-Pousa, Giovanni Grignani, Jean-Yves Blay, Robert Diaz Beveridge, Elena Casiraghi, Silvia Brich, Salvatore Lorenzo Renne, Laura Bergamaschi, Barbara Vergani, Marta Sbaraglia, Paolo Giovanni Casali, Licia Rivoltini, Silvia Stacchiotti, Alessandro Gronchi
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-08-01
Col·lecció:	EBioMedicine
Matèries:	Soft tissue sarcomas Tumour immune microenvironment Neoadjuvant chemotherapy Anthracycline
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S235239642400255X
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