Cardiomyopathy related desmocollin-2 prodomain variants affect the intracellular cadherin transport and processing
BackgroundArrhythmogenic cardiomyopathy can be caused by genetic variants in desmosomal cadherins. Since cardiac desmosomal cadherins are crucial for cell-cell-adhesion, their correct localization at the plasma membrane is essential.MethodsNine desmocollin-2 variants at five positions from various p...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2023-05-01
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| Seria: | Frontiers in Cardiovascular Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1127261/full |
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