Revisiting T-cell adhesion molecules as potential targets for cancer immunotherapy: CD226 and CD2

Abstract Cancer immunotherapy aims to initiate or amplify immune responses that eliminate cancer cells and create immune memory to prevent relapse. Immune checkpoint inhibitors (ICIs), which target coinhibitory receptors on immune effector cells, such as CTLA-4 and PD-(L)1, have made significant str...

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Hlavní autoři:	Yunju Jo, Hye-In Sim, Bohwan Yun, Yoon Park, Hyung-seung Jin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2024-10-01
Edice:	Experimental and Molecular Medicine
On-line přístup:	https://doi.org/10.1038/s12276-024-01317-9
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