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Assessing the Efficiency of Double-Strand Break Repair Mediated by Homologous Recombination and Non-homologous End-Joining Pathways in Saccharomyces cerevisiae

The DNA double-strand breaks (DSBs) generated by exogenous and endogenous factors are repaired by two pathways: homologous recombination (HR) and non-homologous end-joining (NHEJ). These two pathways compete for DSB repair, and the choice of pathway depends on the context of the DNA lesion, the stag...

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Principais autores: Sugith Badugu, Kshitiza Dhyani, Kalappa Muniyappa
格式: Artigo
语言:Inglês
出版: Bio-protocol LLC 2025-07-01
丛编:Bio-Protocol
在线阅读:https://bio-protocol.org/en/bpdetail?id=5378&type=0
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