Atypical cofilin signaling drives dendritic cell migration through the extracellular matrix via nuclear deformation

Summary: To mount an adaptive immune response, dendritic cells must migrate to lymph nodes to present antigens to T cells. Critical to 3D migration is the nucleus, which is the size-limiting barrier for migration through the extracellular matrix. Here, we show that inflammatory activation of dendrit...

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Bibliografische gegevens

Hoofdauteurs:	Harry Warner, Giulia Franciosa, Guus van der Borg, Britt Coenen, Felix Faas, Claire Koenig, Rinse de Boer, René Classens, Sjors Maassen, Maksim V. Baranov, Shweta Mahajan, Deepti Dabral, Frans Bianchi, Niek van Hilten, Herre Jelger Risselada, Wouter H. Roos, Jesper Velgaard Olsen, Laia Querol Cano, Geert van den Bogaart
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2024-03-01
Reeks:	Cell Reports
Onderwerpen:	CP: Cell biology
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2211124724001943
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