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Inducible expression of catalytically active type 1 serine/threonine protein phosphatase in a human carcinoma cell line

<p>Abstract</p> <p>Background </p> <p>One of the major cellular serine/threonine protein phosphatases is protein phosphatase type 1 (PP1). Studies employing many eukaryotic systems all point to a crucial role for PP1 activity in controlling cell cycle progression. One physiological substrate for PP1...

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Principais autores: Klover Peter, Messing Edward M, Sowden Mark P, Reeder Jay E, Villa-Moruzzi Emma, Ludlow John W
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2003-07-01
Serier:Cancer Cell International
Fag:
Type 1 protein phosphatase
retinoblastoma protein
serine/threonine dephosphorylation
phosphatase activity
inducible protein expression
Online adgang:http://www.cancerci.com/content/3/1/12
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