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Clinical application and impact of metagenomic next-generation sequencing for the diagnosis of infectious diseases in severely immunocompromised pediatric patients

Abstract Background Accurate and rapid microbiological diagnosis is essential for the identification and management of critically ill children experiencing immunocompromised (ICH) conditions. Metagenomic next-generation sequencing (mNGS) has shown promising applications in diagnosing infectious dise...

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Principais autores: Huili Shen, Xiaolei Zhang, Bingxue Hu, Yixue Wang, Bin Yang, Panpan Fan, Jing Liu, Zhenyu Zhang, Weiming Chen, Liming He, Weiguo Yang, Guoping Lu, Gangfeng Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-11-01
coleção:BMC Pediatrics
Assuntos:
Diagnosis
Pediatric
Intensive care unit
Immunocompromised
Infection
Metagenomic next-generation sequencing (mNGS)
Acesso em linha:https://doi.org/10.1186/s12887-025-06338-5
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