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TFP5-Mediated CDK5 Activity Inhibition Improves Diabetic Nephropathy via NGF/Sirt1 Regulating Axis

Diabetic nephropathy (DN) is one of the leading causes of chronic kidney disease (CKD), during which hyperglycemia is composed of the major force for the deterioration to end-stage renal disease (ESRD). However, the underlying mechanism triggering the effect of hyperglycemia on DN is not very clear...

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Auteurs principaux: Shi-Lu Cao, Hong-Yan Luo, Yong-Cai Gao, Xiao-Mei Lan, Shun-Yao Liu, Bo Li, Li Bao, Jing E., Danna Ma, Guo-Qing Zhang, Li-Rong Yang, Xi Bao, Ya-Li Zheng
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-07-01
Collection:Frontiers in Cell and Developmental Biology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fcell.2022.829067/full
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