ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

Bacillus subtilis ParB forms multimeric networks involving non-specific DNA binding leading to DNA condensation. Previously, we found that an excess of the free C-terminal domain (CTD) of ParB impeded DNA condensation or promoted decondensation of pre-assembled networks (Fisher et al., 2017). Howeve...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Julene Madariaga-Marcos, Cesar L Pastrana, Gemma LM Fisher, Mark Simon Dillingham, Fernando Moreno-Herrero
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2019-03-01
coleção:	eLife
Assuntos:	ParB single molecule magnetic tweezers TIRF microscopy bacterial chromosome dynamics Spo0J
Acesso em linha:	https://elifesciences.org/articles/43812
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!