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Neurofilament light and glial fibrillary acidic protein do not reflect neuronal or glial damage during different intracranial radiotherapy regimes: a pilot study

IntroductionNeurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) have been shown to be non-specific markers of central nervous system damage and have been associated with the occurrence of primary or secondary brain tumours. However, the response of these markers to cerebral ra...

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Main Authors: Yvonne Dzierma, Holger Sebb, Michael Utzig, Nurlan Abdullayev, Christian Berdel, Christian Ruebe, Jochen Fleckenstein, Markus Hecht, Guido Hildebrandt, Mathias Jucker, Kristina Heyne
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-06-01
Series:Frontiers in Oncology
Subjects:
glial fibrillary acidic protein (GFAP)
neurofilament light (NfL)
neurooncology
radiotherapy
stereotactic radiosurgery
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2026.1745704/full
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