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Innate CD8 T-cells as a potential predictive biomarker for deep molecular response in chronic myeloid leukemia patients

Abstract In chronic myeloid leukemia (CML), the role of immune effectors has been suggested in the achievement of a sustained deep molecular response (DMR) and treatment-free remission (TFR) after tyrosine kinase inhibitor (TKI) discontinuation. A contributory role of the distinct new innate CD8 T-c...

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I tiakina i:
Ngā kaituhi matua: Emilie Cayssials, Lucie Lefèvre, Amandine Decroos, Florence Jacomet, Nathalie Piccirilli, Florence Tartarin, François Guilhot, Jean-Claude Chomel, Philippe Rousselot, Franck E. Nicolini, Stéphanie Ragot, Jean-Marc Gombert, Lydia Roy, André Herbelin, Alice Barbarin
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Springer 2025-12-01
Rangatū:Cancer Immunology, Immunotherapy
Ngā marau:
Chronic myeloid leukemia
Deep molecular response
Immune biomarker
Innate CD8 T-cell
Urunga tuihono:https://doi.org/10.1007/s00262-025-04256-0
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