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The Flagellin:Allergen Fusion Protein rFlaA:Betv1 Induces a MyD88− and MAPK-Dependent Activation of Glucose Metabolism in Macrophages

TLR5 ligand flagellin-containing fusion proteins are potential vaccine candidates for many diseases. A recombinant fusion protein of flagellin A and the major birch pollen allergen Bet v 1 (rFlaA:Betv1) modulates immune responses in vitro and in vivo. We studied the effects of rFlaA:Betv1 on bone ma...

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Autori principali: Yen-Ju Lin, Garibald Papp, Csaba Miskey, Anna Fiedler, Alexandra Goretzki, Sonja Wolfheimer, Jennifer Zimmermann, Peter Crauwels, Zoltán Ivics, Ger van Zandbergen, Stefan Vieths, Stephan Scheurer, Stefan Schülke
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-10-01
Serie:Cells
Soggetti:
flagellin
TLR5
allergen
Bet v 1
fusion protein
metabolism
Accesso online:https://www.mdpi.com/2073-4409/10/10/2614
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