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Skeletal stem/progenitor cells provide the niche for extramedullary hematopoiesis in spleen

In bone marrow, the niche which supports hematopoiesis and nurtures hematopoietic stem cells (HSCs) contains perivascular reticular cells representing a subset of skeletal stem/progenitor cells (SSPCs). These stromal cells which provide the niche are lost or become inadequate during stress, disease...

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Bibliografiske detaljer
Principais autores: Helen C. O’Neill, Hong Kiat Lim
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-03-01
Serier:Frontiers in Physiology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphys.2023.1148414/full
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