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Sevoflurane promotes premature differentiation of dopaminergic neurons in hiPSC-derived midbrain organoids

Background: Conventional animal models used in corresponding basic studies are distinct from humans in terms of the brain’s development trajectory, tissue cytoarchitecture and cell types, making it difficult to accurately evaluate the potential adverse effects of anesthetic treatments on human fetal...

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Autori principali: Jia Shang, Bin Li, Han Fan, Peidi Liu, Wen Zhao, Tao Chen, Pu Chen, Longqiu Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-09-01
Serie:Frontiers in Cell and Developmental Biology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fcell.2022.941984/full
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