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Iron Metabolism Genes Shape the Course of Liver Fibrosis in Chronic Hepatitis C: From Disease Progression to Reversal After Direct-Acting Antivirals Treatment

Chronic hepatitis C (CHC) is linked to iron overload, which significantly correlates with liver fibrosis. This study aimed to assess whether genetic polymorphisms related to iron metabolism are associated with fibrosis severity, predict improvement in fibrosis after HCV clearance with direct-acting...

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Principais autores: Joana Ferreira, Manuel Bicho, Paula Faustino, Fátima Serejo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-09-01
coleção:Viruses
Assuntos:
Chronic hepatitis C
fibrosis
iron metabolism
oxidative stress
genetic polymorphism
direct-acting antivirals
Acesso em linha:https://www.mdpi.com/1999-4915/17/10/1302
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