Melanogenesis and MITF expression in primary melanomas: an immunohistochemical study

Abstract Background The Microphthalmia-associated transcription factor - MITF is a key regulator of melanogenesis, controlling melanin production and pigment phenotype in melanocytes. It also influences cell differentiation, proliferation, and survival. In melanoma, MITF immunohistochemical expressi...

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Главные авторы:	Karina Munhoz de Paula Alves Coelho, Jaqueline Stall, Rodrigo Blasius, Bruna Louise Silva, Hercílio Fronza Junior, Paulo Henrique Condeixa de França
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-02-01
Серии:	Surgical and Experimental Pathology
Предметы:	Melanoma Tumor pigmentation Immunohistochemistry MITF Histological subtype
Online-ссылка:	https://doi.org/10.1186/s42047-026-00223-w
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