The amount of Nck rather than N-WASP correlates with the rate of actin-based motility of Vaccinia virus
ABSTRACT Vaccinia virus exiting from host cells activates Src/Abl kinases to phosphorylate A36, an integral membrane viral protein. Phosphorylated A36 binds the adaptors Nck and Grb2, which recruit N-WASP to activate Arp2/3-driven actin polymerization to promote viral spread. A36 also recruits inter...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2023-12-01
|
| Schriftenreihe: | Microbiology Spectrum |
| Schlagworte: | |
| Online-Zugang: | https://journals.asm.org/doi/10.1128/spectrum.01529-23 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|