F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair

Abstract Scarring is an insurmountable obstacle for axonal regeneration in recovery from spinal cord injury (SCI). It impedes the repair effects of therapeutic targets in cortical neurons, such as PTEN−/− and hyper-IL-6, which cannot break through dense scar barriers to reconstruct neural circuits....

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Xu Xu, Feng Gao, Qixin Chen, Bairu Chen, Wenyu Liang, Runzhi Huang, Yuchen Liu, Zhibo Liu, Yanjing Zhu, Gufa Lin, Bei Ma, Letao Yang, Shaorong Gao, Rongrong Zhu, Liming Cheng
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Publishing Group 2025-08-01
Rangatū:	Signal Transduction and Targeted Therapy
Urunga tuihono:	https://doi.org/10.1038/s41392-025-02354-0
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!