The NLRP3 inflammasome in urogenital cancers: structure, dual function, and therapeutic potential

The NLRP3 inflammasome is a multi-subunit complex consisting of the NLRP3 receptor protein, apoptosis-associated speck-like protein (ASC), and the effector protein caspase-1. The activation mechanisms of the NLRP3 inflammasome are diverse and complex, primarily involving both classical and non-class...

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Autori principali:	Weiming Sun, Ruiting Ma, Rui Zhao, Jiaju Tian, Wenhui Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-07-01
Serie:	Frontiers in Oncology
Soggetti:	NLRP3 inflammasome urogenital cancer activation mechanism targeted therapy
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1593774/full
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