Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia

Abstract Background Oxidative stress and damage are associated with a number of ageing phenotypes, including age‐related loss of muscle mass and reduced contractile function (sarcopenia). Our group and others have reported loss of neuromuscular junction (NMJ) integrity and increased denervation as i...

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Bibliografische gegevens

Hoofdauteurs:	Hongyang Xu, Rojina Ranjit, Arlan Richardson, Holly Van Remmen
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2021-12-01
Reeks:	Journal of Cachexia, Sarcopenia and Muscle
Onderwerpen:	Skeletal muscle Mitochondria Neuromuscular junction ROS Oxidative stress Catalase
Online toegang:	https://doi.org/10.1002/jcsm.12768
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