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A systematic approach to designing statistically powerful heteroscedastic 2 × 2 factorial studies while minimizing financial costs

Abstract Background The 2 × 2 factorial design is widely used for assessing the existence of interaction and the extent of generalizability of two factors where each factor had only two levels. Accordingly, research problems associated with the main effects and interaction effects can be analyzed wi...

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Main Authors: Show-Li Jan, Gwowen Shieh
Format: Artigo
Language:Inglês
Published: BMC 2016-08-01
Series:BMC Medical Research Methodology
Subjects:
Budget
Factorial design
Heteroscedasticity
Interaction
Power
Sample size
Online Access:http://link.springer.com/article/10.1186/s12874-016-0214-3
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