Development of a liquid chromatography–tandem mass spectrometry method for 4-aminobenzoic acid ethyl ester–derivatized glycosaminoglycans and its application to synovial fluid

A novel liquid chromatography–tandem mass spectrometry (LC-MS/MS) in HILIC-mode method for quantitative analysis of glycosaminoglycan (GAG) disaccharides derivatized with 4-aminobenzoic acid ethyl ester was developed. The method enables highly sensitive and selective analysis of 19 GAG-derived disac...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Kengo Hirai, Takamasa Ishii, Hoyun Eom, Riho Takado, Kyohei Higashi, Yusuke Iwasaki, Rie Ito, Nobuaki Higashi, Hiroshi Akiyama
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2026-05-01
Σειρά:	Journal of Chromatography Open
Θέματα:	Glycosaminoglycans 4-aminobenzoic acid ethyl ester derivatization LC-MS/MS Synovial fluid Sulfated disaccharides
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2772391726000198
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