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Targeting MYCN in Molecularly Defined Malignant Brain Tumors

Misregulation of MYC genes, causing MYC overexpression or protein stabilization, is frequently found in malignant brain tumors highlighting their important roles as oncogenes. Brain tumors in children are the most lethal of all pediatric malignancies and the most common malignant primary adult brain...

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Bibliographic Details
Main Authors: Anna Borgenvik, Matko Čančer, Sonja Hutter, Fredrik J. Swartling
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.626751/full
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