Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes
<p>Abstract</p> <p>Background</p> <p>The RNA-dependent RNA polymerase of Influenza A virus is a determinant of viral pathogenicity and host range that is responsible for transcribing and replicating the negative sense segmented viral genome (vRNA). Transcription produces capped and polyadenylated mR...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2006-08-01
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| Serier: | Virology Journal |
| Online adgang: | http://www.virologyj.com/content/3/1/58 |
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