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Experimental study on the relationship between levodopa ⁃induced dyskinesia and phosphorylation of ERK in the striatum

Objective To explore the relationship between levodopa⁃induced dyskinesia (LID) and phosphorylated extracellular signal ⁃ regulated kinase (ERK, Thr202/Tyr204, ERK1/2) in striatum. Methods The hemiparkinsonian rat model was produced by stereotaxically injecting 6⁃hydroxydopamine (6⁃ OHDA) to right m...

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Principais autores: Lu SONG, Yaping MA, Zhenguo LIU, Maowen BA, Leisi BIAN
Formato: Artigo
Idioma:Inglês
Publicado em: Tianjin Huanhu Hospital 2011-02-01
coleção:Chinese Journal of Contemporary Neurology and Neurosurgery
Assuntos:
Parkinson disease
Dyskinesia, drug ⁃ induced
Protein kinases
Fluorescent antibody technique
Levodopa
Acesso em linha:http://www.cjcnn.org/index.php/cjcnn/article/view/315
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