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Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells.

Butanol (C4H10OH) has been used both to dissect the molecular targets of alcohols/general anesthetics and to implicate phospholipase D (PLD) signaling in a variety of cellular functions including neurotransmitter and hormone exocytosis. Like other primary alcohols, 1-butanol is a substrate for PLD a...

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Autori principali: Sarah McDavid, Mary Beth Bauer, Rebecca L Brindley, Mark L Jewell, Kevin P M Currie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0109203&type=printable
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