LGR6 protects against myocardial ischemia-reperfusion injury via suppressing necroptosis

Regulated necrosis (necroptosis) and apoptosis are important biological features of ischemia-reperfusion (I/R) injury. However, the molecular mechanisms underlying myocardial necroptosis remain elusive. Leucine rich repeat containing G protein-coupled receptor 6 (LGR6) has been reported to play impo...

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Auteurs principaux:	Mengmeng Zhao, Zihui Zheng, Jianfang Liu, Yao Xu, Jishou Zhang, Shanshan Peng, Juan-Juan Qin, Jun Wan, Menglong Wang
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2024-12-01
Collection:	Redox Biology
Sujets:	LGR6 Necroptosis ZBP1 STAT2 Myocardial ischemia-reperfusion injury
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2213231724003781
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