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Current status and challenges of immunotherapy in ALK rearranged NSCLC

Rearrangements of the anaplastic lymphoma kinase (ALK) gene account for 5-6% in non-small cell lung cancer (NSCLC). ALK rearranged NSCLC is sensitive to ALK tyrosine kinase inhibitors (TKIs) but prone to drug resistance. Meanwhile, ALK rearranged NSCLC has poor response to single immunotherapy. Here...

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Autori principali: Rongbin Qi, Yingying Yu, Mo Shen, Dongqing Lv, Susu He
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-12-01
Serie:Frontiers in Oncology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2022.1016869/full
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