Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation

This work is one of our efforts to discover potent anticancer agents. We modified the most promising derivative of our previous work concerned with the development of VEGFR-2 inhibitor candidates. Thirteen new compounds based on benzoxazole moiety were synthesized and evaluated against three human c...

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Библиографические подробности

Главные авторы:	Alaa Elwan, Abdallah E. Abdallah, Hazem A. Mahdy, Mohammed A. Dahab, Mohammed S. Taghour, Eslam B. Elkaeed, Ahmed B. M. Mehany, Ahmed Nabeeh, Mohammed Adel, Aisha A. Alsfouk, Hazem Elkady, Ibrahim H. Eissa
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-08-01
Серии:	Molecules
Предметы:	anticancer benzoxazole molecular modeling VEGFR-2 kinase
Online-ссылка:	https://www.mdpi.com/1420-3049/27/15/5047
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