High-fat diet impairs the dendritic morphology of hippocampal CA1 pyramidal neurons in male but not female mice

BackgroundObesity is associated with cognitive function impairment. We previously found that male, but not female, mice have poorer performance in learning and memory tasks and impaired hippocampal synaptic plasticity after long-term high-fat diet (HFD) consumption, compared to regular chow-fed coun...

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Autors principals:	Shu-Fang Teng, Ming Tatt Lee, Li-Jen Lee, Ling-Ling Hwang, Ching-Ping Chen, Hsin-Jung Lee, Chiung-Tong Chen, Lih-Chu Chiou
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-11-01
Col·lecció:	Frontiers in Nutrition
Matèries:	high-fat diet sex difference dendritic spine density dendritic arbor hippocampal CA1 neurons
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1687060/full
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