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Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3-triazole

Muramyl dipeptide (MDP) is the smallest peptidoglycan fragment able to trigger the immune response. Structural modification of MDP can lead to the preparation of analogs with improved immunostimulant properties, including desmuramyl peptides (DMPs). The aim of this work was to prepare the desmuramyl...

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Principais autores: Vesna Petrović Peroković, Željka Car, Josip Draženović, Ranko Stojković, Lidija Milković, Mariastefania Antica, Đani Škalamera, Srđanka Tomić, Rosana Ribić
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-10-01
Serier:Molecules
Fag:
mannose
desmuramyl peptide
adamantyl-triazole
immunostimulant activity
Online adgang:https://www.mdpi.com/1420-3049/26/21/6352
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