Functional Equivalence of Retroviral MA Domains in Facilitating Psi RNA Binding Specificity by Gag

Retroviruses specifically package full-length, dimeric genomic RNA (gRNA) even in the presence of a vast excess of cellular RNA. The “psi” (Ψ) element within the 5′-untranslated region (5′UTR) of gRNA is critical for packaging through interaction with the nucleocapsid (NC) domain of Gag. However, in...

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Bibliografiske detaljer

Principais autores:	Tiffiny Rye-McCurdy, Erik D. Olson, Shuohui Liu, Christiana Binkley, Joshua-Paolo Reyes, Brian R. Thompson, John M. Flanagan, Leslie J. Parent, Karin Musier-Forsyth
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2016-09-01
Serier:	Viruses
Fag:	Rous sarcoma virus (RSV) human immunodeficiency virus type 1 (HIV-1) Gag Psi RNA (Ψ RNA) matrix (MA) nucleocapsid (NC)
Online adgang:	http://www.mdpi.com/1999-4915/8/9/256
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