EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B

Abstract Background Chromosomal instability (CIN), a hallmark of cancer, is commonly linked to poor prognosis in high‐grade prostate cancer (PCa). Paradoxically, excessively high levels of CIN may impair cancer cell viability. Consequently, understanding how tumours adapt to CIN is critical for iden...

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Detalhes bibliográficos

Principais autores:	Yuyang Zhang, Mingqin Su, Yiming Chen, Li Cui, Wei Xia, Renfang Xu, Dong Xue, Xiansheng Zhang, Xingliang Feng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-01-01
coleção:	Clinical and Translational Medicine
Assuntos:	Aurora B CIN CUL3 EHMT2
Acesso em linha:	https://doi.org/10.1002/ctm2.70164
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