A five-residue motif for the design of domain swapping in proteins
Designing interfaces that can induce protein-protein interactions is a challenging problem. Here the authors show that a five amino acid sequence known to mediate domain swapping in cystatins can drive oligomerization when grafted onto functionally and structurally unrelated host proteins, providing...
Gardado en:
| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2019-01-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-019-08295-x |
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