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Guhong Injection Alleviates Cerebral Ischemia–Reperfusion Injury via the PKC/HIF-1α Pathway in Rats

Guhong injection (GHI) is a drug for ischemic stroke created by combining safflower, a traditional Chinese medicine, and aceglutamide, a Western medicine. In this study, we investigated the curative effect of GHI on cerebral ischemia–reperfusion (I/R) injury via the PKC/HIF-1α pathway in rats. Adult...

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Principais autores: Li Yu, Yangyang Zhang, Xixi Zhao, Haitong Wan, Yu He, Weifeng Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-09-01
coleção:Frontiers in Pharmacology
Assuntos:
Guhong injection
cerebral ischemia-reperfusion injury
PKC–protein kinase C
HIF–hypoxia inducible factor
pathway
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2021.716121/full
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