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NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury

Neutrophils are armed with both oxidant-dependent and –independent pathways for killing pathogens. Activation of the phagocyte NADPH oxidase constitutes an emergency response to infectious threat and results in the generation of antimicrobial reactive oxidants. In addition, NADPH oxidase activation...

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Principais autores: Nikolaos eAlmyroudis, Melissa eGrimm, Bruce eDavidson, Marc eRohm, Constantin eUrban, Brahm eSegal
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013-03-01
Serier:Frontiers in Immunology
Fag:
Inflammation
NADPH Oxidase
Host defense
injury
NETs
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00045/full
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