Accurate profiling of single-cell alternative transcript start sites by correcting RNA degradation

Abstract The generation of transcript variants via alternative utilisation of transcription start sites (TSSs) is a pivotal regulatory mechanism in physiological and pathological states. Recent advancements in 5’ single-cell RNA sequencing (scRNA-seq) have enabled TSS analysis at the single-cell lev...

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Bibliografiske detaljer

Principais autores:	Zijie Xu, Zhen Zhou, Chao Tang, Yating Zhang, Bin Mao, Yiming Zhang, Li Chen, Dan Zhang, Junwei Song, Xiuran Zheng, Defu Liu, Huiying Wang, Zhifeng He, Tingfeng Chen, Jing-wen Lin, Lu Chen
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2026-04-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-026-72298-8
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