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Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

During development, proliferation must be tightly controlled for organs to reach their appropriate size. While the Hippo signaling pathway plays a major role in organ growth control, how it senses and responds to increased cell density is still unclear. In this study, we use the zebrafish lateral li...

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Principais autores: Sobhika Agarwala, Sandra Duquesne, Kun Liu, Anton Boehm, Lin Grimm, Sandra Link, Sabine König, Stefan Eimer, Olaf Ronneberger, Virginie Lecaudey
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2015-09-01
Serier:eLife
Fag:
Amotl2
Hippo
proliferation
organ size
Yap1
Lef1
Online adgang:https://elifesciences.org/articles/08201
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