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Development of an efficient mice model of cancer‐associated cardiac cachexia

Abstract Background Cancer‐associated cardiac cachexia (CACC) refers to cardiac injury in cancer patients in a malignant state, but preclinical animal models remain inadequately developed. Methods This study established CACC models in C57BL/6J and BALB/c mice using orthotopic, intra‐abdominal, and h...

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Autori principali: Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2025-11-01
Serie:Animal Models and Experimental Medicine
Soggetti:
cachexia
cardiac atrophy
contractility
myocardial myosin
onco‐cardiology
Accesso online:https://doi.org/10.1002/ame2.70060
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