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A systems model for immune cell interactions unravels the mechanism of inflammation in human skin.

Inflammation is characterized by altered cytokine levels produced by cell populations in a highly interdependent manner. To elucidate the mechanism of an inflammatory reaction, we have developed a mathematical model for immune cell interactions via the specific, dose-dependent cytokine production ra...

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Detalhes bibliográficos
Principais autores: Najl V Valeyev, Christian Hundhausen, Yoshinori Umezawa, Nikolay V Kotov, Gareth Williams, Alex Clop, Crysanthi Ainali, Christos Ouzounis, Sophia Tsoka, Frank O Nestle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-12-01
Colecção:PLoS Computational Biology
Acesso em linha:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1001024&type=printable
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