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Mucoadhesive Chitosan–Gellan Gum Nanoparticles for Rifampicin Delivery: Taguchi Optimization and In Vitro Release Behavior

<b>Background/Objectives:</b> Tuberculosis treatment remains challenging due to the limited stability and side effects of conventional rifampicin formulations. This study aimed to synthesize and optimize mucoadhesive chitosan–gellan gum nanoparticles for improved rifampicin delivery. The novelty of...

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Furkejuvvon:
Váldodahkkit: Siu-Yin Cheung, Aldana Galiyeva, Yerkeblan Tazhbayev, Tolkyn Zhumagaliyeva, Yuliia Bardadym, Vladimir Aseyev
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2026-05-01
Ráidu:Pharmaceutics
Fáttát:
nanoparticles
chitosan
gellan gum
antituberculosis drug
polyelectrolyte complex coacervation
polysaccharide
Liŋkkat:https://www.mdpi.com/1999-4923/18/5/627
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