Código QR (código de barras bidimensional)

The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathies

In this review article, we present the fascinating story of rapamycin (sirolimus), a drug able to induce γ-globin gene expression and increased production of fetal hemoglobin (HbF) in erythroid cells, including primary erythroid precursor cells (ErPCs) isolated from β-thalassemia patients. For this...

Fuld beskrivelse

Na minha lista:
Principais autores: Roberto Gambari, Cristina Zuccato, Lucia Carmela Cosenza, Matteo Zurlo, Jessica Gasparello, Alessia Finotti, Maria Rita Gamberini, Marco Prosdocimi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-09-01
Serier:Biology
Fag:
β-thalassemia
γ-globin genes
rapamycin (sirolimus)
fetal hemoglobin
clinical trials
Online adgang:https://www.mdpi.com/2079-7737/12/9/1202
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker