Spatiotemporal Characterization of Human Early Intervertebral Disc Formation at Single‐Cell Resolution

Abstract The intervertebral disc (IVD) acts as a fibrocartilaginous joint to anchor adjacent vertebrae. Although several studies have demonstrated the cellular heterogeneity of adult mature IVDs, a single‐cell transcriptomic atlas mapping early IVD formation is still lacking. Here, the authors gener...

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Hlavní autoři:	Taifeng Zhou, Yu Chen, Zhiheng Liao, Long Zhang, Deying Su, Zhuling Li, Xiaoming Yang, Xiaona Ke, Hengyu Liu, Yuyu Chen, Ricong Weng, Huimin Shen, Caixia Xu, Yong Wan, Ren Xu, Peiqiang Su
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2023-05-01
Edice:	Advanced Science
Témata:	annulus fibrosus intervertebral disc formation notochord nucleus pulposus single‐cell RNA sequencing
On-line přístup:	https://doi.org/10.1002/advs.202206296
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