Calibration of Flow Cytometers Enables Reproducible Measurements of Extracellular Vesicle Concentrations and Reference Range Establishment

ABSTRACT The concentration of cells is a key component of modern blood tests. Given the biomarker potential of extracellular vesicles (EVs) in blood, we aimed to establish reference ranges for blood cell‐derived EVs using flow cytometry. To address the orders‐of‐magnitude variability in reported EV...

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Autores principales:	Britta A. Bettin, Bo Li, Kim Falkena, Ton G. vanLeeuwen, Christian Gollwitzer, Zoltán Varga, Nadine Ajzenberg, Jovan P. Antovic, Pascale Berckmans, Edit I. Buzas, Randy P. Carney, Sean Cook, Françoise Dignat‐George, Dorothee Faille, Bernd Giebel, Jennifer C. Jones, Yohan Kim, Romaric Lacroix, Joanne Lannigan, Fabrice Lucien, Katariina Maaninka, Erika G. Marques deMenezes, Annette Meyer, Rachel R. Mizenko, Inge Nelissen, John Nolan, Philip J. Norris, Desmond Pink, Sumeet Poudel, Stéphane Robert, Pia R.‐M. Siljander, Vera A. Tang, Tobias Tertel, Tina Van Den Broeck, Lili Wang, Joshua A. Welsh, Rienk Nieuwland, Edwin van derPol
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2025-12-01
Colección:	Journal of Extracellular Vesicles
Materias:	blood plasma calibration extracellular vesicles flow cytometry reference ranges reproducibility
Acceso en línea:	https://doi.org/10.1002/jev2.70189
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