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Hypoxia-cleavable and specific targeted nanomedicine delivers epigenetic drugs for enhanced treatment of breast cancer and bone metastasis

Abstract Breast cancer bone metastasis has become a common cancer type that still lacks an effective treatment method. Although epigenetic drugs have demonstrated promise in cancer therapy, their nontargeted accumulation and drug resistance remain nonnegligible limiting factors. Herein, we first fou...

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Gardado en:
Principais autores: Zhaofeng Li, Peixin Liu, Wei Chen, Xueying Liu, Fan Tong, Junhui Sun, Yang Zhou, Ting Lei, Wenqin Yang, Dong Ma, Huile Gao, Yi Qin
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2023-07-01
Series:Journal of Nanobiotechnology
Assuntos:
Bone metastasis
Epigenetic drug
Nanomedicine
Drug delivery
Hypoxia responsive
Acceso en liña:https://doi.org/10.1186/s12951-023-01939-7
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