Single-cell-derived ferroptosis signature predicts prognosis and therapy response in esophageal squamous cell carcinoma

BackgroundEsophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with poor prognosis and limited therapeutic options. Ferroptosis, a regulated form of cell death characterized by iron-dependent lipid peroxidation, plays a crucial role in tumor progression and immune regulation....

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Autori principali:	Qin Xu, Yu Ma, Xuanqi Huang, Elyar abdukirim, Meng Yang, Chunli Song, Meng Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-07-01
Serie:	Frontiers in Oncology
Soggetti:	esophageal squamous cell carcinoma ferroptosis prognostic model single-cell RNA sequencing therapy
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1873687/full
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